Services

The Apelles team matches the service requirements of our clients with the core expertise our founding members.  When projects go beyond our domains, we partner with a select group of carefully chosen companies and consultants that have each provide their unique service.  Each of these partners possess our same level of excellence, flexibility, and service-based approach. 

The services provided by the members of Apelles Partners include –

• Lead Identification   (XTAL)         
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• Lead Optimization   (XTAL)    
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• Target Validation  (XTAL)   
• In-vitro Assay Development and Assessment (SBH / pION)
  • Cytokine Bioassay Services
    Cytokine and Biomarker ELISA Kits
    Biomarker/Molecular Diagnostics Development
• Protein Production and Purification (SBH)
  • Recombinant Cytokines, Monoclonal Antibodies, and Antigen-Affinity Purified Polyclonal Antibodies
• PK/PD Studies – invitro ADME (pION)
  • HTS – early/late invitro ADME 
• In-Vivo Animal Models/Animal PK/PD
• Screening & Hits-to-Lead
• Organic & Medicinal Chemistry
• Pre-Formulation & Drug Delivery
• Other Custom Requests

Services provided by the Apelles Consulting Partners:

• Grant Submission Management
• Discovery Consulting/Management
• Preclinical Consulting/Management
• Small Molecule and Biologic Formulation Consulting/Management Services
• CMC Consulting/Management
• CFO, CSO and COO Leadership
• Additional Services Upon Request

Let us know what services and resources you need to best meet your research challenges. 

XTAL Biostructures
XTAL delivers Focused High Quality Technical Research with a unique CRO model that creates extra-ordinary partner value with our pay for service structure and a comprehensive suite of analytical services and products that give a complete 360 degree evaluation of your candidate.
(more)

SBH Sciences
SBH Sciences is a well-established, profitable, and expanding Biotechnology Service Provider company. We provide comprehensive preclinical process development services to the biopharmaceutical, diagnostics and biotechnology industries including cell culture (mammalian and insect cell), protein purification, cell-based assays and ELISA Development Kit. (more)

pION Biopharma Services
We provide pharmaceutical property profiles of your compounds. With this information, performance is improved in lead generation, optimization and selection. We are the world leader in absorption measurements in GIT and BBB – permeability, solubility, dissolution, ionization. (more)